For adults with
Chronic Idiopathic Constipation (CIC)
Going shouldn’t mean
going to extremes

Diarrhea is not efficacy—it’s time to address the age-old tradeoff in CIC.1,2
Now there’s Trulance, the only treatment that is thought to replicate the pH-sensitivity of naturally occurring uroguanylin.3-6*
Trulance provided more regular, well-formed bowel movements.3

*Based on pre-clinical studies. Clinical relevance of this data has not been established.

Results over 12 weeks were statistically significant vs placebo, as shown in 2 Phase 3 clinical studies.3